The interactions (including weak interactions) between dienophiles and dienes play an important role in the Diels-Alder reaction.To elucidate the influence of these interactions on the reactivity, a popular DFT functional and a variational DFT functional corrected Wire Ferrule with dispersion terms are used to investigate different substituent grou
Dissolvable polymeric microneedles loaded with aspirin for antiplatelet aggregation
To reduce mucosal damage in the gastrointestinal tract caused by aspirin, we developed a dissolvable polymeric microneedle (MN) patch loaded with aspirin.Biodegradable polymers provide mechanical strength to the MNs.The MN tips punctured the cuticle of the skin and dissolved when Hoodie and sweatpants set in contact with the subcutaneous tissue.The
A Novel Esthetic Approach using Connective Tissue Graft for Soft Tissue Defect Following Surgical Excision of Gingival Fibrolipoma
The aim of the present case report is to evaluate the adjunctive use of a connective tissue graft to overcome soft tissue defects following excision of a gingival fibrolipoma in the aesthetic region.Connective tissue graft has been well documented for treating defects of esthetic concern.However, the literature does not contain many reports on the